Alpha Synuclein is a protein of 140aa expressed abundantly in the brain. a-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Mutations of the a-synuclein gene have been linked to Parkinson disease.
Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilutions:
Western Blot: 1:1000; Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Positive Controls:
HeLa, 293,...
Alpha Synuclein is a protein of 140aa expressed abundantly in the brain. a-Synuclein is also the main component of pathogenic Lewy bodies and Lewy neurites. Mutations of the a-synuclein gene have been linked to Parkinson disease.
Applications:
Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested.
Recommended Dilutions:
Western Blot: 1:1000; Incubate membrane with diluted antibody in 5% BSA, 1X TBS, 0.1% Tween-20 at 4°C with gentle shaking, overnight.
Immunoprecipitation: 1:50
Optimal dilutions to be determined by the researcher.
Positive Controls:
HeLa, 293,...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Synuclein
APPLICATION
IP WB
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A affinity and peptide affinity chromatography.
PHYSICAL FORM
Supplied as a liquid in 10mM sodium HEPES, pH 7.5, 150mM sodium chloride, 0.1mg/ml BSA, 50% glycerol.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu Mk Mo Rt
IMMUNOGEN
Synthetic peptide corresponding to the C-terminal sequence of human alpha-Synuclein
SPECIFIC ACTIVITY
Recognizes endogenous levels of human alpha-Synuclein at ~18kD. May crossreact with beta synuclein. Species Crossreactivity: rat, mouse and monkey.
SWISS PROT#
P37840
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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