SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Applications:
Suitable for use in ELISA, Western Blot, Immunohistochemistry, Flow Cytometry (Not Tested) and Immunofluorescence . Other applications not tested.
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Flow Cytometry (Not Tested): 1:10~1:50
Immunofluorescence:...
SMAD4 is the common SMAD (co-SMAD)mediator of signal transduction by TGF-beta (transforming growth factor). It promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. It may act as a tumor suppressor.
Applications:
Suitable for use in ELISA, Western Blot, Immunohistochemistry, Flow Cytometry (Not Tested) and Immunofluorescence . Other applications not tested.
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:50-1:100
Flow Cytometry (Not Tested): 1:10~1:50
Immunofluorescence:...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Smad Proteins
APPLICATION
E IF IHC WB
ACCESSION#
NP_005350
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by ammonium sulfate precipitation.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
GRADE
Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
Synthetic peptide selected from the C-terminal region of human SMAD4 (KLH).
SPECIFIC ACTIVITY
Recognizes human SMAD4.
SWISS PROT#
Q13485
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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