SHB is an adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. It may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. It may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades, and may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended...
SHB is an adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. It may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. It may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades, and may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
Applications:
Suitable for use in ELISA and Immunohistochemistry. Other applications not tested.
Recommended...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
ISOTYPE
IgG
CROSS REACTIVITY
Hu
CLASS
Polyclonal Antibodies
SUBCLASS
Stem Cell Research
APPLICATION
E IHC
ACCESSION#
NP_003019
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by ammonium sulfate precipitation.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein isothiocyanate (FITC).
GRADE
Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
IMMUNOGEN
Synthetic peptide selected from the N-term region of human SHB (KLH).
SPECIFIC ACTIVITY
Recognizes human SHB.
SWISS PROT#
Q15464
COMMODITY CODE
30021010
HOST
rabbit
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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