Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:16,000
Western Blot: 1-3ug/ml, observed in lysates of cell line Jurkat on ~45kD bands
Optimal dilutions to be determined by the researcher.
Storage...
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. The G(s) protein is involved in hormonal regulation of adenylate cyclase: it activates the cyclase in response to beta-adrenergic stimuli. XLas isoforms interact with the same set of receptors as Gnas isoforms.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:16,000
Western Blot: 1-3ug/ml, observed in lysates of cell line Jurkat on ~45kD bands
Optimal dilutions to be determined by the researcher.
Storage...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
G Proteins
APPLICATION
E WB
ACCESSION#
NP_000507.1, NP_001070956.1, NP_001070957.1
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Bo Hu Mo Rt
IMMUNOGEN
Synthetic peptide corresponding to C-QAARSNSDGEKATK, from human GNAS, at the internal region of the protein (NP_000507.1, NP_001070956.1, NP_001070957.1).
SPECIFIC ACTIVITY
Recognizes human GNAS. Species sequence homology: Bovine, mouse and rat.
COMMODITY CODE
30021010
HOST
goat
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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