Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-13, Mol. Wt. 40-80kD) and Sodium glucose co-transporter-1 (SGLT-1, 662 amino acids; ~75kD). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N- and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may...
Most mammalian cells transport glucose through a family of membrane proteins known as glucose transporters. Molecular cloning of these glucose transporters has identified a family of closely related genes that encodes at least 7 proteins (Glut-1 to Glut-13, Mol. Wt. 40-80kD) and Sodium glucose co-transporter-1 (SGLT-1, 662 amino acids; ~75kD). Individual member of this family have identical predicted secondary structures with 12 transmembrane domains. Both N- and C-termini are predicted to be cytoplasmic. Most differences in sequence homology exist within the four hydrophilic domains that may...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Glucose Transporters
APPLICATION
E
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Serum
PHYSICAL FORM
Supplied as a liquid in PBS, 0.05% sodium azide.
GRADE
Serum
ANTIBODY TYPE
Pab
HOST SPECIES
mouse
ISOTYPE
IgG
CROSS REACTIVITY
Bo Hu Mo Po Rb Rt
IMMUNOGEN
12aa peptide sequence near the C-terminal, cytoplasmic domain of mouse GLUT 1, conjugated to KLH. Cellular Localization: Cell membrane; Localizes primarily at the cell surface. Species Sequence Homology: 100% conserved in human, rat, rabbit, bovine and porcine; 90% in chicken.
SPECIFIC ACTIVITY
Recognizes mouse Glut-1. No significant sequence homology with other Glut proteins.
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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