The lentivirus FIV, responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency Virus (HIV), is a complex retrovirus with a tightly-packed genome, containing the structural genes gag, env and pro-pol and the accessory genes vif, rev and ORF-A/2.
Applications:
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested.
Recommended Dilution:
Immunohistochemistry: Frozen sections. Sensitive to formaldehyde fixation and tissue processing. Use acetone fixation for frozen...
The lentivirus FIV, responsible for a progressive and debilitating immune deficiency syndrome in domestic cats, similar to that caused by the human Immunodeficiency Virus (HIV), is a complex retrovirus with a tightly-packed genome, containing the structural genes gag, env and pro-pol and the accessory genes vif, rev and ORF-A/2.
Applications:
Suitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications have not been tested.
Recommended Dilution:
Immunohistochemistry: Frozen sections. Sensitive to formaldehyde fixation and tissue processing. Use acetone fixation for frozen...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
SUBCLASS
Infectious Disease FIV
APPLICATION
E IHC WB
CLONE NUMBER
10C215 (PAK3-2C1)
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A affinity chromatography from tissue culture supernatant.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.
GRADE
Affinity Purified
ANTIBODY TYPE
Mab
ISOTYPE
IgG1
SPECIFIC ACTIVITY
Recognizes an immunodominant p24 epitope of Feline Immunodeficiency Virus p24 gag. The specific binding epitope recognized appears to be enclosed in a tight peptide coil during gag production and maturation. The addition of 0.3% Triton-X detergent is recommended to reveal this epitope for antibody binding. Detects a dominant band of ~24kD, and also detects p24 gag precursor bands at 36, 39, 49 and 52kD under reducing conditions in Western Blot. Does not recognize Feline Leukaemia Virus (FeLV), Feline Herpes Virus (FHV) type 1, Feline Coronavirus or Feline Calicivirus.
COMMODITY CODE
30021010
HOST
mouse
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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