erbB4 (c-erbB4, HER4) (APC)
SKU / CAT#: E3451-40M-APC-100ul
$95100
usd$951.00
erbB4 (c-erbB4, HER4) (APC)
United States Biological CorpSKU / CAT#: E3451-40M-APC-100ul
MPN: E3451-40M-APC-100ul
$95100
usd$951.00
Available
SHIPS Mar 5th
Available
SHIPS Mar 5th
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Description
erbB4/HER4 is the fourth member of the human epidermal growth factor receptor (EGFR) family that is frequently overexpressed in a variety of aggressive epithelial carcinomas. Its extracellular domain is most similar to the orphan receptor HER3, whereas its cytoplasmic kinase domain exhibits 79% and 77% identity with EGFR and HER2, respectively. HER4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain and cerebellum.
Applications:
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications...
erbB4/HER4 is the fourth member of the human epidermal growth factor receptor (EGFR) family that is frequently overexpressed in a variety of aggressive epithelial carcinomas. Its extracellular domain is most similar to the orphan receptor HER3, whereas its cytoplasmic kinase domain exhibits 79% and 77% identity with EGFR and HER2, respectively. HER4 is most predominantly expressed in several breast carcinoma cell lines, and in normal skeletal muscle, heart, pituitary, brain and cerebellum.
Applications:
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Monoclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified
APPLICATION
IHC IP WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide and a stabilizer. Labeled with Allophycocyanin (APC).
SUBCLASS
Oncoproteins
CLONE NUMBER
9H232 (HFR1/2G4)
HOST SPECIES
human
ISOTYPE
IgG2b
IMMUNOGEN
Synthetic peptide sequence RSTLQHPDYLQEYST from the cytoplasmic domain of the protein, residues 1250-1264. Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein. Species sequence homology: mouse.
ACCESSION#
NM_001005915.1
ANTIBODY TYPE
Mab
GRADE
Purified
CROSS REACTIVITY
Hu Mo Rt
SPECIFIC ACTIVITY
Recognizes human c-erB-4/Her 4 cytoplasmic domain of the protein (residues 1250-1264), a member of the EGF receptor (type 1) family involved in cell growth regulation. Expression or function may be altered in human cancers.
Species Crossreactivity: rat.
COMMODITY CODE
30021010
HOST
mouse
SWISS PROT#
Q15303
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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