Apolipoprotein AI promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein AI is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77aa; an 18aa signal peptide is removed co-translationally and a 6aa propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL...
Apolipoprotein AI promotes cholesterol efflux from tissues to the liver for excretion. Apolipoprotein AI is the major protein component of high density lipoprotein (HDL) in the plasma. Synthesized in the liver and small intestine, it consists of two identical chains of 77aa; an 18aa signal peptide is removed co-translationally and a 6aa propeptide is cleaved post-translationally. Apolipoprotein A I is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Lipoproteins
APPLICATION
E WB
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid in 10mM Tris, 0.15M sodium chloride, 1mM EDTA, pH 8.0, 0.02% sodium azide.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
mouse
ISOTYPE
IgG
CROSS REACTIVITY
Mo Rt
IMMUNOGEN
Apolipoprotein AI from pooled mouse plasma high density lipoprotein.
SPECIFIC ACTIVITY
Recognizes mouse Apo AI. Does not react well with human Apo AI. Species Crossreactivity: rat
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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