DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:1000-1:5000
Western Blot: 1:200-1:1000
Optimal...
DTX3 functions as an E3 ubiquitin ligase. It is regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Applications:
Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution:
ELISA: 1:1000-1:5000
Western Blot: 1:200-1:1000
Optimal...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
APPLICATION
E IHC WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.4, 0.05% sodium azide, 40% glycerol.
SUBCLASS
Ubiquitin Ligases
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
Fusion protein of human DTX3
ANTIBODY TYPE
Pab
GRADE
Affinity Purified
CROSS REACTIVITY
Hu Mo
SPECIFIC ACTIVITY
Human, Mouse
COMMODITY CODE
30021010
HOST
rabbit
SWISS PROT#
Q8N9I9
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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