MED27 (Mediator of RNA Polymerase II Transcription Subunit 27, Cofactor Required for Sp1 Transcriptional Activation Subunit 8, CRSP Complex Subunit 8, Mediator Complex Subunit 27, P37 TRAP/SMCC/PC2 Subunit, Transcriptional Coactivator CRSP34, MED27, CRSP34) (FITC)

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended...