PSMA6 (27 a prosomal Protein, IOTA, Macropain iota Chain, Macropain Subunit iota, MGC22756, MGC2333, MGC23846, Multicatalytic endopeptidase Complex iota Chain, p27K, PROS 27, PROS-27, PROS27, Prosomal P27K Protein, Proteasome (prosome macropain) Subunit alpha Type 6, Proteasome iota Chain, Proteasome Subunit alpha Type 6, Proteasome Subunit alpha Type-6, Proteasome Subunit iota, PSA6, PSMA 6, PSMA6)

The proteasome represents a large protein complex that exists inside all eukaryotes and archaea, and in some bacteria. The main function of proteasomes is to degrade unnecessary or damaged proteins by proteolysis. The most common form of the proteasome, known as the 26S Proteasome, contains one 20S Proteasome core particle structure and two 19S regulatory caps. The 20S Proteasome core is hollow and forms an enclosed cavity, where proteins are degraded, as well as openings at the two ends to allow the target protein to enter. The 20S Proteasome core particle contains many subunits, depending on...