Hox-D8 (Homeobox Protein Hox-D8, Homeobox Protein Hox-4E, Homeobox Protein Hox-5.4, Name: HOXD8, HOX4E, Hox-5.4)

The Hox proteins are a family of transcription factors that play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Hox proteins are involved in controlling axial patterning, leukemias and hereditary malformations. HoxD8 (homeobox D8), also known as HOX4E, is a 290 amino acid protein that localizes to the nucleus and contains one homeobox DNA-binding domain. One of several...