FBL (34 Nucleolar scleroderma Antigen, 34 a Nucleolar scleroderma Antigen, 34- Nucleolar scleroderma Antigen, FBL, FBRL, FIB, FIB1, FLRN, Nop1p, RNA U3 Small Nucleolar interacting Protein 1, RNU3IP1, rRNA 2' O Methyltransferase fibrillarin, rRNA 2'-O-Methyltransferase fibrillarin)

Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in pre-ribosomal RNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA. Applications: Suitable for use in Western Blot, Immunohistochemistry. Other applications not tested. Recommended Dilution: Western Blot: 1:500-1:2000 Immunohistochemistry: 1:50-1:200 Optimal dilutions to be determined by the researcher. Storage...