Elk1, phosphorylated (T417) (ELK 1, Elk1, ELK1 Member of ETS OncoGene Family, ELK1 Protein, ELK2 Member of ETS OncoGene Family, ETS Domain Containing Protein Elk 1, ETS Domain Containing Protein Elk1, ETS Domain Protein Elk1, ETS Domain-Containing Protein Elk-1, ETS like Gene 1, Member of ETS OncoGene Family, OncoGene Elk1, Tyrosine Kinase (ELK1) OncoGene)

Ets-1 is the prototype member of a family of genes identified on the basis of homology to the v-Ets oncogene isolated from the E26 erythroblastosis virus. This family of genes currently includes Ets-1, Ets-2, Erg-1–3, Elk-1, Elf-1, Elf-5, NERF, PU.1, PEA3, ERM, FEV, ER8l, Fli-1, TEL, Spi-B, ESE-1, ESE-3A, Net, ABT1 and ERF. Members of the Ets gene family exhibit varied patterns of tissue expression, and share a highly conserved carboxy-terminal domain containing a sequence related to the SV40 large T antigen nuclear localization signal sequence. This conserved domain is essential for Ets-1 binding...