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DIAPH1 (DIAPH1, deafness, autosomal dominant 1, DFNA1, DIA1, DIAP1, DIAP1_HUMAN, DIAPH1, Diaphanous Homolog 1 (Drosophila), diaphanous Homolog 1, Diaphanous Related formin 1, Diaphanous-Related formin-1, DRF1, FLJ25265, hDIA1, LFHL1, low frequency hearing loss 1, p140DIA, Protein diaphanous Homolog 1)
SKU / CAT#: 222161-50ul
$48900
usd
$489.00
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  4. DIAPH1 (DIAPH1, deafness, autosomal dominant 1, DFNA1, DIA1, DIAP1, DIAP1_HUMAN, DIAPH1, Diaphanous Homolog 1 (Drosophila), diaphanous Homolog 1, Diaphanous Related formin 1, Diaphanous-Related formin-1, DRF1, FLJ25265, hDIA1, LFHL1, low frequency hearing loss 1, p140DIA, Protein diaphanous Homolog 1)
222161-50ul

DIAPH1 (DIAPH1, deafness, autosomal dominant 1, DFNA1, DIA1, DIAP1, DIAP1_HUMAN, DIAPH1, Diaphanous Homolog 1 (Drosophila), diaphanous Homolog 1, Diaphanous Related formin 1, Diaphanous-Related formin-1, DRF1, FLJ25265, hDIA1, LFHL1, low frequency hearing loss 1, p140DIA, Protein diaphanous Homolog 1)

United States Biological Corp
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SKU / CAT#: 222161-50ul
MPN: 222161-50ul
$48900
usd
$489.00
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
SKU
Unit size / Options
Availability
Price
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Description
Dia 1 (also designated p140mDia) and Dia 2 (also designated p134mDia 2), mammalian homologs of Drosophila Diaphanous, belong to a family of formin-homology (FH) proteins, which are characterized by having tandemly aligned FH1 and FH2 domains in their carboxy terminal regions. The amino terminus of inactivated Dia 1 binds to the FH1 and FH2 domains, and is activated when GTP-bound Rho disrupts the intramolecular interaction of Dia 1 and converts it to an open conformation. Once activated, Dia 1 colocalizes with profilin and RhoA in dynamic plasma-membrane structures, and induces the formation of...
Dia 1 (also designated p140mDia) and Dia 2 (also designated p134mDia 2), mammalian homologs of Drosophila Diaphanous, belong to a family of formin-homology (FH) proteins, which are characterized by having tandemly aligned FH1 and FH2 domains in their carboxy terminal regions. The amino terminus of inactivated Dia 1 binds to the FH1 and FH2 domains, and is activated when GTP-bound Rho disrupts the intramolecular interaction of Dia 1 and converts it to an open conformation. Once activated, Dia 1 colocalizes with profilin and RhoA in dynamic plasma-membrane structures, and induces the formation of...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
Disease Markers
APPLICATION
IHC WB
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by immunoaffinity chromatography.
PHYSICAL FORM
Supplied as a liquid PBS, 0.1% sodium azide, 50% glycerol.
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu Mo Rt
IMMUNOGEN
Recombinant full length Human DIAPH1.
SPECIFIC ACTIVITY
Recognizes endogenous levels of DIAPH1. Species Crossreactivity: Human, mouse, rat
SWISS PROT#
O60610
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Badge
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