COG2 (Brefeldin A Sensitive peripheral Golgi Protein, COG 2, COG Complex Subunit 2, COG2, COG2_HUMAN, Component of oligomeric golgi Complex 2, Conserved oligomeric Golgi Complex Component 2, Conserved oligomeric Golgi Complex Subunit 2, LDLC, Low density lipoProtein Receptor defect C Complementing Protein, Low density lipoProtein Receptor defect C-Complementing Protein, Transcript ch4822,)

The structure and function of the Golgi apparatus is controlled by a number of multi-protein complexes that are involved in glycosylation reactions and vesicular transport. The conserved oligomeric Golgi (COG) complex consists of three subcomplexes, termed LDLC, SEC34 and GTT (Golgi transport complex), all of which contain proteins necessary for proper Golgi operation. COG2 (conserved oligomeric Golgi complex subunit 2), also known as LDLC, is a 730 amino acid component of the COG complex. Localized to the cytoplasmic side of the Golgi apparatus, COG2 is required for proper Golgi morphology and...