SYT1 (Synaptotagmin-1, Synaptotagmin I, SytI, p65, SVP65, SYT, DKFZp781D2042) (FITC)

May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended...