IGSF6 (DORA, Immunoglobulin Superfamily Member 6, Protein DORA)

IGSF6 (DORA), a novel member of the immunoglobulin superfamily (IGSF) from human and rat expressed in dendritic and myeloid cells. Using a probe from the open reading frame of the rat cDNA, we isolated a cosmid which contains the entire mouse gene. By comparative analysis and reverse transcriptase polymerase chain reaction, we defined the intron/exon structure and the mRNA of the mouse gene and, with respect to human BAC clones, the human gene. The genes span 10Kb (mouse) and 12Kb (human), with six exons arranged in a manner similar to other members of the IGSF. All intron/exon boundaries follow...