CD109 is a GPI-anchored member of the A2-macroglobulin (A2M) and complement family of proteins. Mature human CD109 contains a bait region with recognition sequences for multiple proteases, an internal thioester bond, and a domain similar to the receptor binding domain of A2M. Cleavage of A2M family proteins within the bait region activates the thioester bond to promote covalent bonding to nucleophilic groups in adjacent molecules. Within the region included in the recombinant protein used for immunization, human CD109 shares 71%-73% aa sequence identity with mouse and rat CD109. CD109 is expressed...
CD109 is a GPI-anchored member of the A2-macroglobulin (A2M) and complement family of proteins. Mature human CD109 contains a bait region with recognition sequences for multiple proteases, an internal thioester bond, and a domain similar to the receptor binding domain of A2M. Cleavage of A2M family proteins within the bait region activates the thioester bond to promote covalent bonding to nucleophilic groups in adjacent molecules. Within the region included in the recombinant protein used for immunization, human CD109 shares 71%-73% aa sequence identity with mouse and rat CD109. CD109 is expressed...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
SUBCLASS
CD Markers
APPLICATION
WB
ACCESSION#
BC152996, AAI52997.1
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A affinity chromatography.
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).
GRADE
Affinity Purified
ANTIBODY TYPE
Pab
HOST SPECIES
human
ISOTYPE
IgG
CROSS REACTIVITY
Hu
IMMUNOGEN
Full length human CD109, aa1-1445 (AAI52997.1).
SPECIFIC ACTIVITY
Recognizes human CD109.
COMMODITY CODE
30021010
HOST
rabbit
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
4°C Do Not Freeze
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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