This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this...
This gene encodes the receptor for type 1 gonadotropin-releasing hormone. This receptor is a member of the seven-transmembrane, G-protein coupled receptor (GPCR) family. It is expressed on the surface of pituitary gonadotrope cells as well as lymphocytes, breast, ovary, and prostate. Following binding of gonadotropin-releasing hormone, the receptor associates with G-proteins that activate a phosphatidylinositol-calcium second messenger system. Activation of the receptor ultimately causes the release of gonadotropic luteinizing hormone (LH) and follicle stimulating hormone (FSH). Defects in this...
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Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
CLASS
Polyclonal Antibodies
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
Purified by Protein A and peptide affinity chromatography.
APPLICATION
E WB
PHYSICAL FORM
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
SUBCLASS
Receptors
HOST SPECIES
human
ISOTYPE
IgG
IMMUNOGEN
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 49-77 in the N-terminal region of human GNRHR, UniProt Accession #P30968
ACCESSION#
NP_000397
ANTIBODY TYPE
Pab
GRADE
Affinity Purified
CROSS REACTIVITY
Hu
SPECIFIC ACTIVITY
Recognizes human GNRHR.
COMMODITY CODE
30021010
HOST
rabbit
SWISS PROT#
P30968
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
-20°C
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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