Q-dextran 4 kDa

Carbohydrates

Sweden

For Research Use Only (RUO)

• Cationic tracer studies: Q-dextran has a much stronger net charge than the corresponding DEAE-dextran and will thus give enhanced responses in systems where this effect is important. • Surface Modification: Researchers functionalizing surfaces (e.g., biosensors, biomaterials) benefit from Q-dextran’s ability to introduce stable, positive surface charges. • Complexation and Binding Studies: Ideal for creating complexes with nucleic acids or proteins to study binding kinetics, surface adsorption, or biomolecular interactions. • Cellular Uptake and Endocytosis Studies: Cationic charge enhances the uptake by endocytosis, useful for modeling drug delivery and nanoparticle entry into cells. • Transfection Research: Historically used in mammalian cell DNA transfection experiments, Q-dextran still finds niche use where simple, non-viral gene delivery is studied. • Protein Purification: Q-dextran is a proven choice for ion-exchange chromatography workflows, helping isolate or fractionate proteins under mild, biocompatible conditions. • Vaccine Adjuvant Studies: Studied as a component in vaccine formulations to enhance immune system targeting by improving antigen presentation.

4 kDa (QD4)

ISO 9001, ECOVADIS SUSTAINABILITY RATING SILVER

Dextran Derivatives

Polysucrose is supplied as a white powder, ensuring easy handling and long-term storage.

Quaternary Ammonium Groups: Provides strong, permanent positive charge to facilitate binding to negatively charged membranes and biomolecules like proteins, and nucleic acids. High Solubility: Fully water-soluble powder, allows rapid and easy preparation for chromatography, formulation, or complexation protocols. Flexible Application Range: Multiple molecular weights allow researchers to study size-dependent effects in binding studies. High Lot-to-Lot Consistency: Manufactured with controlled degree of functionalization and tight molecular weight distribution for reproducibility across experiments.