TMS Protection of Alcohols using Azidotrimethylsilane
Regioselective Bromination of Fused Pyridine N-Oxides
Typical Procedure:
To a mixture of tetrabutylammonium bromide (1.5 eq.), 4Å molecular sieves and the appropriate fused pyridine N-oxide is added CH2Cl2 (0.01M) and the mixture is stirred at room temperature for 10 min. p-Toluenesulfonic anhydride (1.5 eq.) is added and the reaction is stirred at room temperature overnight. The reaction mixture is filtered and concentrated under reduced pressure. The crude product is purified by flash column chromatography using hexanes/CH2Cl2 and hexanes/EtOAc solvent mixtures.
Di-Anionic Alkyl Zincates as Transmetalators in Negishi Cross-Coupling
P501 : Dispose of contents/ container to an approved waste disposal plant.
P270 : Do not eat, drink or smoke when using this product.
P264 : Wash skin thoroughly after handling.
P280 : Wear protective gloves/ eye protection/ face protection.
P337 + P313 : If eye irritation persists: Get medical advice/ attention.
P305 + P351 + P338 : IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P302 + P352 : IF ON SKIN: Wash with plenty of soap and water.
P332 + P313 : If skin irritation occurs: Get medical advice/ attention.
P362 : Take off contaminated clothing and wash before reuse.
P301 + P312 + P330 : IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. Rinse mouth.
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
PURITY
>98.0%(T)
PHYSICAL FORM
Solid
MWCO (kDa)
322.38
QUALITY CERTIFICATION / COMPLIANCE
Fukaya factory is certified for GMP, ISO14001:2004 (JQA-EM5386) and IQ Net (JP-JQA-EM5386).
APPEARANCE
White to Almost white powder to crystaline
MOLECULAR FORMULA
C16H36BrN
SDBS (AIST SPECTRAL DB)
3131.0
HS NUMBER
2923.90.0100
PURITY / ANALYSIS METHOD
>98.0%(T)
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Shipping & Handling
Shipped In
Ambient
Safety & Storage
Storage Temperature
See product label for specific storage conditions.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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