Pharmaceutical Ingredients (for Research and Experimental Use)
SUBCLASS
Antidiabetic Ingredients (for Research and Experimental Use)
COUNTRY OF ORIGIN
Japan
APPLICATION
Mitiglinide Calcium: A Fast-Acting Insulin-Releasing Agent
Mitiglinide calcium (KAD-1229; s 21403) is a glitinide class non-sulfonylurea insulinotropic agent with rapid onset. More rapidly than that of sulfonylurea antidiabetics, mitiglinide inhibits ATP-gated K+ channels and thereby causes depolarization of the B-cell membrane. The depolarization leads to activation of voltage-dependent Ca channels and Ca2+ influx into the B-cell, and eventually increases insulin release. For your reference, [O0471] is a synthetic intermediate of mitiglinide. (The product is for research purpose only.)
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.