MAPK4 Antibody (pSer186): FITC

Polyclonal

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Canada

WB, AM

https://www.ncbi.nlm.nih.gov/gene/5596

NP_002738

Non-hazardous

Non-hazardous

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

WB (1:250); optimal dilutions for assays should be determined by the user.

Rabbit

Human

FITC

Peptide Affinity Purified

ISO 9001:2015

MAPK4 (pSer186)

A phospho-specific peptide corresponding to residues surrounding Ser186 of human MAPK4 (AA183-190)

Detects 62.623 kDa.

PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated

https://antibodyregistry.org/search.php?q=AB_2707979

Cytoplasm | Nucleus

Highly expressed in heart and brain.

MAPK4 is a protein-serine/threonine kinase that phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK4/MAPK4 is phosphorylated at Ser-186 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK4/MAPK4. MAPK4 may promote entry in the cell cycle.

Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | MAPK Pathway | Cancer

ERK4 Antibody, ERK3 Antibody, ERK3 related Antibody, MAPK4 Antibody, Extracellular signal regulated kinase 4 Antibody, MAP kinase 4 Antibody, MAP kinase isoform p63 Antibody, MAPK4 Antibody, Mitogen activated protein kinase 4 Antibody, MK04_HUMAN Antibody, p63MAPK Antibody, PRKM4 Antibody