Specifications
SHIPPING NOTES
Blue Ice or 4ºC. All orders received in North America by 12:00 PM PST Monday to Thursday will usually be shipped out on the same day. North American customers will typically receive their orders within 1-2 business days. All shipments are F.O.B. from point of shipment, pre-paid and added to the invoice. Freight charges include but not limited to: priority service and packaging materials.Products are shipped with “cold packs” in insulated containers. There is a charge for this packaging and for the shipping costs via FedEx. Please inspect packages immediately upon receipt and inform Labscoop Customer Support of any shortage or damage within 48 hours of receipt. We can only accept returns after we have given prior authorization and issued specific shipping instructions. If a customer wishes to use their own FedEx account number please indicate this on the purchase order or during checkout.
GENE ID
https://www.ncbi.nlm.nih.gov/gene/5591
*USAGE / SAFETY STATEMENT
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
ANTIBODY TYPE
WB (1:250); optimal dilutions for assays should be determined by the user.
PURIFICATION
Peptide Affinity Purified
QUALITY CERTIFICATION / COMPLIANCE
ISO 9001:2015
GENE ALIAS
DNA PKcs (pTyr883)
IMMUNOGEN
A phospho-specific peptide corresponding to residues surrounding Tyr883 of human DNA PKcs (AA880-886)
SPECIFICITY
Detects 469.14 kDa.
STORAGE BUFFER
PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
ANTIBODY ID
https://antibodyregistry.org/search.php?q=AB_2707629
CELLUAR LOCALIZATIONS
Nucleus
SCIENTIFIC BACKGROUND
DNA PKcs is encoded by the gene PRKDC which is a protein-serine/threonine kinase. Its mutation pattern in human tumours is very characteristic of a tumour suppressor protein.
RESEARCH AREA
Cell Signaling | Epigenetics and Nuclear Signaling | DNA/RNA | DNA Damage and Repair | Non Homologous End Joining | Cell Signaling | Epigenetics and Nuclear Signaling | DNA/RNA | DNA Damage and Repair | DNA Damage Recognition
ALTERNATIVE NAMES
DNA dependent protein kinase catalytic subunit Antibody, DNA-PK catalytic subunit Antibody, DNAPK Antibody, DNPK 1 Antibody, HYRC 1 Antibody, IMD26 Antibody, p350 Antibody, p460 Antibodyy, PKRDC Antibody, Protein Kinase DNA Activated Catalytic Polypeptide Antibodyy, XRCC 7 Antibody
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