ZM447439

Small Molecules

Inhibitor

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Canada

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Non-hazardous

Non-hazardous

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

Orange solid

≥98% (TLC)

ISO 9001:2015

ZM447439 is a potent and selective inhibitor of Aurora B kinase. ZM447439 induces cell growth arrest mid-way through mitosis, and therefore effectively activates apoptosis.

1. Walsby E., Walsh V., Pepper C., Burnett A., & Mills K. (2008) Haematologica. 93(5): 662–669. 2. Kim K.W., et al. (2007) Int. J. Rad.Oncol. Biol. Phy. 67(5): 1519–1525.

Cell Signaling | Cancer | Apoptosis | Cancer Growth Inhibitors | Tyrosine Kinase Inhibitors

ZM 447439, N-[4-[[6-Methoxy-7-[3-(4-morpholinyl)propoxy]-4-quinazolinyl]amino]phenyl]benzamide