HC-030031

Small Molecules

Inhibitor

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Canada

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Non-hazardous

Non-hazardous

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

White solid

>98%

ISO 9001:2015

Selective TRPA1 channel blocker that antagonizes AITC-and formalin-evoked calcium influx. Doe not block currents mediated by TRPV1, V3, V4, hERG or Nav1.2 channels (1-2).

1. McNamara C.R., et al. (2007) Proc Natl Acad Sci USA. 104(33): 13525-13530. 2. Taylor-Clark T.E., et al. (2008) Mol Pharmacol. 73(2): 274-281.

Neuroscience | Ion Channels | Transient Receptor Potential (TRP) Channels

2-(1,3-Dimethyl-2,6-dioxo-1,2,3,6-tetrahydro-7H-purin-7-yl)-N-(4-isopropylphenyl)acetamide