VEGF is a cytokine that possesses potent growth and angiogenic properties. It has the ability to stimulate the survival and proliferation of endothelial cells, promote vascular permeability and angiogenesis. VEGF is expressed in vascularized tissues and is known to play a crucial role in both normal and pathological angiogenesis. There is significant evidence that implicates VEGF in the development of intra-ocular neovascular syndromes and tumor metastasis. VEGF signals through three receptors, namely fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene...
VEGF is a cytokine that possesses potent growth and angiogenic properties. It has the ability to stimulate the survival and proliferation of endothelial cells, promote vascular permeability and angiogenesis. VEGF is expressed in vascularized tissues and is known to play a crucial role in both normal and pathological angiogenesis. There is significant evidence that implicates VEGF in the development of intra-ocular neovascular syndromes and tumor metastasis. VEGF signals through three receptors, namely fms-like tyrosine kinase (flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene...
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