Dystrophin Antibody / DMD
SKU / CAT#: V8862SAF-100UG
$49900
usd
$4.99/UG
V8862SAF-100UG

Dystrophin Antibody / DMD

NSJ Bioreagents
SKU / CAT#: V8862SAF-100UG
MPN: V8862SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 6th
Available
SHIPS Jul 6th
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Description
Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin...
Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the DMD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This DMD antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
*USAGE / SAFETY STATEMENT
This DMD antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
SUBCLASS
Monoclonal
UNIPROT ID
P11532
CLONE NUMBER
DMD/3676
APPLICATION.1
ELISA, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein A/G affinity
IMMUNOGEN
A portion of amino acids 114-263 from the human protein was used as the immunogen for the DMD antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
ELISA (order BSA-free format for coating),Immunohistochemistry (FFPE): 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the DMD antibody should be determined by the researcher.
LOCALIZATION
Cell surface, Cytoplasm
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human skeletal muscle tissue with DMD antibody (clone DMD/3676). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human skeletal muscle tissue with DMD antibody (clone DMD/3676). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human heart muscle tissue with DMD antibody (clone DMD/3676). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
+1
SDS-PAGE analysis of purified, BSA-free DMD antibody (clone DMD/3676) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the DMD antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This DMD antibody is available for research use only.
Regulatory & Compliance
Badge
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