IL1 alpha Antibody / IL1A
SKU / CAT#: V8700-100UG
$49900
usd
$4.99/UG
V8700-100UG

IL1 alpha Antibody / IL1A

NSJ Bioreagents
SKU / CAT#: V8700-100UG
MPN: V8700-100UG
$49900
usd
$4.99/UG
Available
SHIPS May 12th
Available
SHIPS May 12th
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Description
Two forms of interleukin-1, designated IL-1 alpha and beta, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1a and IL-1b bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer...
Two forms of interleukin-1, designated IL-1 alpha and beta, have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1a and IL-1b bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer...
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Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the IL1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This IL1A antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P01583
CLONE NUMBER
IL1A/3981
*USAGE / SAFETY STATEMENT
This IL1A antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A portion of amino acids 113-271 from the human protein was used as the immunogen for the IL1A antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the IL1A antibody should be determined by the researcher.
LOCALIZATION
Secreted
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Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using IL1A antibody. These results demonstrate the foremost specificity of the IL1A/3981 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
Analysis of HuProt(TM) microarray containing more than 19,000 full-length human proteins using IL1A antibody. These results demonstrate the foremost specificity of the IL1A/3981 mAb. Z- and S- score: The Z-score represents the strength of a signal that an antibody (in combination with a fluorescently-tagged anti-IgG secondary Ab) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If the targets on the HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-scores. The S-score therefore represents the relative target specificity of an Ab to its intended target.
IHC staining of FFPE human colon carcinoma with IL1A antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free IL1A antibody as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the IL1A antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This IL1A antibody is available for research use only.
Regulatory & Compliance
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