SOX11 Antibody
SKU / CAT#: V8688SAF-100UG
$49900
usd
$4.99/UG
V8688SAF-100UG

SOX11 Antibody

NSJ Bioreagents
SKU / CAT#: V8688SAF-100UG
MPN: V8688SAF-100UG
$49900
usd
$4.99/UG
Available
SHIPS Mar 13th
Available
SHIPS Mar 13th
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Description
Recognizes a protein of ~47kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker...
Recognizes a protein of ~47kDa, identified as SOX11. This MAb is highly specific and does not cross-react with other members of the SOX-family. Mantle cell lymphoma (MCL) accounts for 5% to 10% of mature B-cell neoplasms and is an aggressive disease genetically characterized by overexpression of Cyclin D1. Cyclin D1 overexpression is the hallmark of MCL. However, approximately 5%-10% of MCLs lack Cyclin D1 expression and may be misdiagnosed. Almost all Cyclin D1-positive as well as Cyclin D1-negative MCL, show overexpression of SOX-11. The detection of this transcription factor is a useful biomarker...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant SOX11 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant SOX11 antibody is available for research use only.
Regulatory & Compliance
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Specifications
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
P35716
CLONE NUMBER
SOX11/3235R
*USAGE / SAFETY STATEMENT
This recombinant SOX11 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
IHC-P
HOST SPECIES
Rabbit
ISOTYPE
Rabbit IgG, kappa
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Rabbit Monoclonal
PURIFICATION
Protein A affinity chromatography
IMMUNOGEN
A portion of amino acids 300-400 from the human protein was used as the immunogen for the recombinant SOX11 antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
Immunohistochemistry (FFPE): 2-4ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the recombinant SOX11 antibody should be determined by the researcher.
LOCALIZATION
Nuclear, cytoplasmic
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human mantle cell lymphoma with recombinant SOX11 antibody (clone SOX11/3235R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human mantle cell lymphoma with recombinant SOX11 antibody (clone SOX11/3235R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human cervical carcinoma with recombinant SOX11 antibody (clone SOX11/3235R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant SOX11 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant SOX11 antibody is available for research use only.
Regulatory & Compliance
Badge
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