MBP Antibody / Myelin Basic Protein
SKU / CAT#: V8680-100UG
$49900
usd
$4.99/UG
V8680-100UG

MBP Antibody / Myelin Basic Protein

NSJ Bioreagents
SKU / CAT#: V8680-100UG
MPN: V8680-100UG
$49900
usd
$4.99/UG
Available
SHIPS Mar 17th
Available
SHIPS Mar 17th
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Description
Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission...
Myelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission...
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Safety & Storage
Storage Temperature
Store the Myelin Basic Protein antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Myelin Basic Protein antibody is available for research use only.
Regulatory & Compliance
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Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P02686
CLONE NUMBER
MBP/4276
*USAGE / SAFETY STATEMENT
This Myelin Basic Protein antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
WB, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2a
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A synthetic peptide corresponding to the amino acids surrounding phosphorylated threonine 98 were used as the immunogen for the Myelin Basic Protein antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the Myelin Basic Protein antibody should be determined by the researcher.
LOCALIZATION
Cytoplasm
Questions & Answers (0)
Citations (0)
IHC staining of FFPE human brain with Myelin Basic Protein antibody (clone MBP/4276). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human brain with Myelin Basic Protein antibody (clone MBP/4276). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human brain with Myelin Basic Protein antibody (clone MBP/4276). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
+1
Western blot testing of human brain lysate with Myelin Basic Protein antibody (clone MBP/4276). Isoforms may be visualized from 20~37 kDa.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Myelin Basic Protein antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This Myelin Basic Protein antibody is available for research use only.
Regulatory & Compliance
Badge
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