p40 / deltaNp63 Antibody
SKU / CAT#: V8627BTN
$49900
usd$1.00/UL
p40 / deltaNp63 Antibody
NSJ BioreagentsSKU / CAT#: V8627BTN
MPN: V8627BTN
$49900
usd$1.00/UL
Available
SHIPS Feb 27th
Available
SHIPS Feb 27th
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Description
p63 consists of two major isoforms-TAp63 and delta-Np63. These isoforms differ in the structure of the N-terminal domains. The TAp63 isoform (identified by anti-p63 antibody) contains a transactivation-competent TA domain with homology to p53, which regulates the expression of the growth-inhibitory genes. In contrast, DNp63 isoform (identified by anti-p40 antibody) contains an alternative transcriptionally-inactive delta-N domain, which antagonizes the activity of TAp63 and p53. P40/3980R recognizes exclusively delta-Np63 but not TAp63. p40 is a squamous cell carcinoma specific antibody. It reacts...
p63 consists of two major isoforms-TAp63 and delta-Np63. These isoforms differ in the structure of the N-terminal domains. The TAp63 isoform (identified by anti-p63 antibody) contains a transactivation-competent TA domain with homology to p53, which regulates the expression of the growth-inhibitory genes. In contrast, DNp63 isoform (identified by anti-p40 antibody) contains an alternative transcriptionally-inactive delta-N domain, which antagonizes the activity of TAp63 and p53. P40/3980R recognizes exclusively delta-Np63 but not TAp63. p40 is a squamous cell carcinoma specific antibody. It reacts...
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Shipped In
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Safety & Storage
Storage Temperature
Store the recombinant p40 antibody at 2-8°C (up to one month) or aliquot and store at -20°C (longer term).
Safety Statement
This recombinant p40 antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
*USAGE / SAFETY STATEMENT
This recombinant p40 antibody is available for research use only.
FORMAT
Biotin Conjugate
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
Q9H3D4CLONE NUMBER
rTP40/3690
APPLICATION.1
FACS, IF, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Mouse Monoclonal
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A synthetic peptide from the N-terminal of human p40 protein was used as the immunogen for the recombinant p40 antibody.
STORAGE BUFFER
0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 2-4ug/million cells,Immunofluorescence: 2-4ug/ml,Immunohistochemistry (FFPE): 2-4ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the recombinant p40 antibody should be determined by the researcher.
LOCALIZATION
Nuclear
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant p40 antibody at 2-8°C (up to one month) or aliquot and store at -20°C (longer term).
Safety Statement
This recombinant p40 antibody is available for research use only.
Regulatory & Compliance
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