SOD1 Antibody / Superoxide Dismutase 1
SKU / CAT#: V8624-100UG
$49900
usd
$4.99/UG
V8624-100UG

SOD1 Antibody / Superoxide Dismutase 1

NSJ Bioreagents
SKU / CAT#: V8624-100UG
MPN: V8624-100UG
$49900
usd
$4.99/UG
Available
SHIPS Jul 7th
Available
SHIPS Jul 7th
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Description
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral...
Cu-Zn superoxide dismutase-1 (SOD-1) is a well-characterized cytosolic scavenger of oxygen free radicals that requires copper and zinc binding to potentiate its enzymatic activity. Enzymatically, SOD-1 facilitates the dismutation of oxygen radicals to hydrogen peroxide and also catalyzes pro-oxidant reactions, which include the peroxidase activity and hydroxyl radical generating activity. SOD-1 is ubiquitously expressed in somatic cells and functions as a homodimer. Defects in the gene encoding SOD-1 have been implicated in the progression of neurological diseases, including amyotrophic lateral...
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Safety & Storage
Storage Temperature
Store the SOD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This SOD1 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
P00441
CLONE NUMBER
SOD1/4248
*USAGE / SAFETY STATEMENT
This SOD1 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
FACS, IF, WB, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A portion of amino acids 14-148 from the human protein was used as the immunogen for the SOD1 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml,Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the SOD1 antibody should be determined by the researcher.
LOCALIZATION
Cytoplasmic
Questions & Answers (0)
Citations (0)
Flow cytometry testing of PFA-fixed human MCF7 cells with SOD1 antibody; Red=isotype control, Blue= SOD1 antibody.
Flow cytometry testing of PFA-fixed human MCF7 cells with SOD1 antibody; Red=isotype control, Blue= SOD1 antibody.
IHC staining of FFPE human kidney with SOD1 antibody. HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
+2
Western blot testing of human 1) JEG3 and 2) LNCaP lysate with SOD1 antibody. Predicted molecular weight ~16 kDa.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the SOD1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This SOD1 antibody is available for research use only.
Regulatory & Compliance
Badge
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