TOP1MT Antibody / Topoisomerase I mitochondrial
SKU / CAT#: V8148-100UG
$49900
usd$4.99/UG
TOP1MT Antibody / Topoisomerase I mitochondrial
NSJ BioreagentsSKU / CAT#: V8148-100UG
MPN: V8148-100UG
$49900
usd$4.99/UG
Available
SHIPS Dec 26th
Available
SHIPS Dec 26th
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Description
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium,...
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium,...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TOP1MT antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This TOP1MT antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
*USAGE / SAFETY STATEMENT
This TOP1MT antibody is available for research use only.
FORMAT
Purified
SUBCLASS
Monoclonal
UNIPROT ID
Q969P6CLONE NUMBER
TOP1MT/613
APPLICATION.1
WB, IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2b, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
Recombinant full-length human TOP1MT protein was used as the immunogen for the TOP1MT antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml for 30 minutes at RT
APPLICATION NOTES
Optimal dilution of the TOP1MT antibody should be determined by the researcher.
LOCALIZATION
Cytoplasmic (Mitochondria)
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the TOP1MT antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This TOP1MT antibody is available for research use only.
Regulatory & Compliance
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