SREBP2 Antibody / SREBF2
SKU / CAT#: V8100SAF-100UG
$49900
usd$4.99/UG
SREBP2 Antibody / SREBF2
NSJ BioreagentsSKU / CAT#: V8100SAF-100UG
MPN: V8100SAF-100UG
$49900
usd$4.99/UG
Available
SHIPS Sep 15th
Available
SHIPS Sep 15th
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Description
The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors,...
The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1 (SRE-1). When cellular sterol stores are depleted, the element is activated, the gene is transcribed and the cellular uptake of LDL increases. A set of SREbinding proteins (SREBPs) have been identified, including two basic helixloop-helix-leucine zipper (bHLH-zip) transcription factors,...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the SREBP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This SREBP2 antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
UNIPROT ID
Q12772CLONE NUMBER
SREBP2/1579
*USAGE / SAFETY STATEMENT
This SREBP2 antibody is available for research use only.
FORMAT
Purified (Sodium Azide Free)
APPLICATION.1
ELISA
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A recombinant full-length human protein was used as the immunogen for this SREBP2 antibody.
STORAGE BUFFER
1 mg/ml in 1X PBS; BSA free, sodium azide free
APPLICATION DETAILS
ELISA (order BSA-free format for coating)
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the SREBP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This SREBP2 antibody is available for research use only.
Regulatory & Compliance
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