Cytokeratin 1 Antibody
SKU / CAT#: V7908-20UG
$21900
usd
$10.95/UG
V7908-20UG

Cytokeratin 1 Antibody

NSJ Bioreagents
SKU / CAT#: V7908-20UG
MPN: V7908-20UG
$21900
usd
$10.95/UG
Available
SHIPS Oct 15th
Available
SHIPS Oct 15th
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Description
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
Keratins are a family of intermediate filament proteins that assemble into filaments through forming heterodimers of one type I keratin (keratins 9 to 23) and one type II keratin (keratins 1 to 8). Keratins demonstrate tissue and differentiation specific expression profiles. Cytokeratin 1 is a hetero-tetramer of two type I as well as two type II keratins, keratin-10 (KRT10). Keratin 1 is differentiation specific keratin that is one of the predominant keratins in suprabasal keratinocytes in stratified epithelia. Mutations in keratin 1 cause epidermolytic hyperkeratosis.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the CK1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This CK1 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
CLONE NUMBER
KRT1/1840
*USAGE / SAFETY STATEMENT
This CK1 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2a, kappa
REACTIVITY SPECIES
Human, Rat
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A recombinant full-length human Cytokeratin 1 protein was used as the immunogen for this CK1 antibody.
STORAGE BUFFER
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 2-4ug/ml
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
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IHC staining of FFPE human cervical carcinoma with CK1 antibody (clone KRT1/1840). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human cervical carcinoma with CK1 antibody (clone KRT1/1840). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human skin with CK1 antibody (clone KRT1/1840). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free CK1 antibody (clone KRT1/1840) as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the CK1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This CK1 antibody is available for research use only.
Regulatory & Compliance
Badge
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