Integrin beta 3 Antibody / ITGB3 / CD61
SKU / CAT#: V7895-100UG
$49900
usd
$4.99/UG
V7895-100UG

Integrin beta 3 Antibody / ITGB3 / CD61

NSJ Bioreagents
SKU / CAT#: V7895-100UG
MPN: V7895-100UG
$49900
usd
$4.99/UG
Available
SHIPS Nov 6th
Available
SHIPS Nov 6th
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Description
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the V-chain (CD51) to form vitronectin receptor, or with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears...
Reacts with human integrin beta3 (GPIIIa, vitronectin receptor beta chain). It associates with the V-chain (CD51) to form vitronectin receptor, or with the IIb-chain (CD41) to form the GpIIb/GpIIIa complex (CD41/CD61).The CD41/CD61 complex appears early in megakaryocyte maturation. The activated CD41/CD61 complex is a receptor for von Willebrand factor, soluble fibrinogen, fibronectin, vitronectin and thrombospondin. It plays a central role in platelet activation and aggregation. The CD51/CD61 is implicated in tumor metastasis and adenoviral infection. The antibody detects platelets in smears...
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant ITGB3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant ITGB3 antibody is available for research use only.
Regulatory & Compliance
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Specifications
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
P05106
CLONE NUMBER
rITGB3/2145
*USAGE / SAFETY STATEMENT
This recombinant ITGB3 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Mouse Monoclonal
PURIFICATION
Protein G affinity chromatography
IMMUNOGEN
A recombinant human partial protein (amino acids 385-490) was used as the immunogen for this ITGB3 antibody.
STORAGE BUFFER
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml
APPLICATION NOTES
Optimal dilution of the antibody should be determined by the researcher.
LOCALIZATION
Cell surface, cytoplasmic
Questions & Answers (0)
Citations (0)
IHC testing of FFPE human spleen with recombinant ITGB3 antibody. Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.
IHC testing of FFPE human spleen with recombinant ITGB3 antibody. Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH9, for 10-20 min followed by cooling at RT for 20 min.
SDS-PAGE analysis of purified, BSA-free recombinant ITGB3 antibody as confirmation of integrity and purity.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant ITGB3 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant ITGB3 antibody is available for research use only.
Regulatory & Compliance
Badge
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