TIMP2 Antibody
SKU / CAT#: V7356IHC-7ML
$49900
usd$71.29/ML
TIMP2 Antibody
NSJ BioreagentsSKU / CAT#: V7356IHC-7ML
MPN: V7356IHC-7ML
$49900
usd$71.29/ML
Available
SHIPS May 12th
Available
SHIPS May 12th
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Description
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases 2 (TIMP2). It is closely related to TIMP1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP9 or gelatinase B). TIMP2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant TIMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant TIMP2 antibody is available for research use only.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
HOST SPECIES
Rabbit
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
UNIPROT ID
P16035CLONE NUMBER
TIMP2/2488R
*USAGE / SAFETY STATEMENT
This recombinant TIMP2 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
ISOTYPE
Rabbit IgG, kappa
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Rabbit Monoclonal
PURIFICATION
Protein A affinity chromatography
IMMUNOGEN
Amino acids 56-66 (DSGNDIYGNPI) from the human protein were used as the immunogen for this recombinant TIMP2 antibody.
STORAGE BUFFER
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
APPLICATION DETAILS
The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
APPLICATION NOTES
The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the recombinant TIMP2 antibody to be titered up or down for optimal performance.<br><br>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
LOCALIZATION
Cytoplasmic, cell surface, secreted
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Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant TIMP2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant TIMP2 antibody is available for research use only.
Regulatory & Compliance
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