NKX2.2 Antibody
SKU / CAT#: V7226-20UG
$21900
usd
$10.95/UG
V7226-20UG

NKX2.2 Antibody

NSJ Bioreagents
SKU / CAT#: V7226-20UG
MPN: V7226-20UG
$21900
usd
$10.95/UG
Available
SHIPS Apr 28th
Available
SHIPS Apr 28th
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Description
NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]
NKX2.2 acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter (By similarity). [UniProt]
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant NKX2.2 antibody is available for research use only.
Regulatory & Compliance
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Specifications
CLASS
Primary Antibodies
SUBCLASS
Recombinant Monoclonal
GENE ID
https://www.ncbi.nlm.nih.gov/gene/4821
CLONE NUMBER
RMNK2-1
*USAGE / SAFETY STATEMENT
This recombinant NKX2.2 antibody is available for research use only.
FORMAT
Purified
APPLICATION.1
IHC-P
HOST SPECIES
Rabbit
ISOTYPE
Rabbit IgG, kappa
REACTIVITY SPECIES
Human
CLONALITY
Recombinant Rabbit Monoclonal
PURIFICATION
Protein A affinity chromatography
IMMUNOGEN
A human partial recombinant protein was used as the immunogen for this recombinant NKX2.2 antibody.
STORAGE BUFFER
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
APPLICATION DETAILS
Immunohistochemistry (FFPE): 1-2ug/ml for 30 min at RT, Prediluted IHC only format: incubate for 30 min at RT (1)
APPLICATION NOTES
Titering of the recombinant NKX2.2 antibody may be required for optimal performance.<p>1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
LOCALIZATION
Nuclear
Questions & Answers (0)
Citations (0)
IHC testing of FFPE human pancreas with recombinant NKX2.2 antibody (clone RMNK2-1). HIER: steam sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
IHC testing of FFPE human pancreas with recombinant NKX2.2 antibody (clone RMNK2-1). HIER: steam sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
IHC testing of FFPE Ewings sarcoma with recombinant NKX2.2 antibody (clone RMNK2-1). HIER: steam sections in pH 9 10mM Tris with 1mM EDTA for 10-20 min.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the recombinant NKX2.2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Safety Statement
This recombinant NKX2.2 antibody is available for research use only.
Regulatory & Compliance
Badge
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