labscoop
  • Product
    MarketplaceEverything your lab needs in one place.
    Shared CartStreamlined requisitioning.
    CuratorCurated supplies from product experts.
    Science SamplesDiscover better, cost effective supplies.
  • Enterprise
    SolutionsSupercharge your organization’s eProcurement.
    IntergationsIntegrate your existing ERP & eProcurement.
    OnboardingDrive end user option with ease.
  • Pricing
  • Company
    AboutThe company, our mission and our values.
    Supplier PartnersOur niche and industry leading suppliers.
    CareersJoin us. Be yourself. Drive our mission.
    BlogCompany blog.
    NewsroomGet the latest news and updates.
    Press KitAccess brand assets.
  • Support
Sign in
Create an Account
  • Product
    MarketplaceShared CartScienceSamplesCurator
  • Enterprise
    SolutionsIntegrationsOnboarding
  • Company
    AboutBlogSupplier PartnersCareersNewsroomPress Kit
  • Support
    Help CenterFAQsSchedule a DemoReport a BugMake a Suggestion
logosupport@labscoop.com800 316 3081
Terms of UseTerms & Conditions of SalePrivacy Policy
© Labscoop LLC. All rights reserved

EN
usaUSA
© Labscoop LLCTerms of UseTerms & Conditions of SalePrivacy Policy
EN
usaUSA
Ku70 + Ku80 Antibody
SKU / CAT#: V7202PE-100T
$49900
usd
$4.99/TESTS
  1. Home
  2. Life Science
  3. Antibodies
  4. Ku70 + Ku80 Antibody
V7202PE-100T

Ku70 + Ku80 Antibody

NSJ Bioreagents
Write a review
0
0citationscitations
0
0questionsquestions
0
SKU / CAT#: V7202PE-100T
MPN: V7202PE-100T
$49900
usd
$4.99/TESTS
Available
SHIPS Jun 2nd
Available
SHIPS Jun 2nd
SKU
Unit size / Options
Availability
Price
No products found
Description
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki]
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Ku70 + Ku80 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Safety Statement
This Ku70 + Ku80 antibody is available for research use only.
Regulatory & Compliance
Badge
Technical Documents
Datasheet (1)
UwdQdku70-ku80-antibody-pe-conjugate-lkap1-1-v7202pe
Specifications
CLASS
Primary Antibodies
SUBCLASS
Monoclonal
GENE ID
https://www.ncbi.nlm.nih.gov/gene/2547
CLONE NUMBER
LKAP1-1
*USAGE / SAFETY STATEMENT
This Ku70 + Ku80 antibody is available for research use only.
FORMAT
PE Conjugate
APPLICATION.1
FACS
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG1, kappa
REACTIVITY SPECIES
Human
CLONALITY
Monoclonal (mouse origin)
PURIFICATION
Protein G purified
IMMUNOGEN
A human cell nuclear fraction was used as the immunogen for this Ku70 + Ku80 antibody.
STORAGE BUFFER
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
APPLICATION DETAILS
Flow cytometry: 5ul/test/million cells in 100ul or 5ul/100ul whole blood
APPLICATION NOTES
Titering of the Ku70 + Ku80 antibody may be required for optimal performance.
LOCALIZATION
Nuclear
Questions & Answers (0)
Citations (0)
Intracellular FACS testing of K562 cells with PE conjugated Ku70 + Ku80 antibody (red) and isotype control (green).
Intracellular FACS testing of K562 cells with PE conjugated Ku70 + Ku80 antibody (red) and isotype control (green).
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store the Ku70 + Ku80 antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Safety Statement
This Ku70 + Ku80 antibody is available for research use only.
Regulatory & Compliance
Badge
Science SamplesWe’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
Join BETA

Join Our List

mail
Subscribe to the Scoop blog and get the latest updates on life in the lab.
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
Related Blog Articles
Related Categories
Related Blog Articles