Integrin beta 3 Antibody
SKU / CAT#: R30709
$41900
usd
$4.19/UG
R30709

Integrin beta 3 Antibody

NSJ Bioreagents
$41900
usd
$4.19/UG
Available
SHIPS Apr 6th
Available
SHIPS Apr 6th
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Description
ITGB3 (Integrin beta 3), also called GP3A, GPIIIa, CD61, is a protein that in humans is encoded by the ITGB3 gene. It is a cluster of differentiation found on thrombocytes. The ITGB3 complex belongs to the integrin class of cell adhesion molecule receptors that share a common heterodimeric structure with alpha and beta subunits. The ITGB3 complex mediates platelet aggregation by acting as a receptor for fibrinogen. Although the protein is expressed on the cell surface at normal levels and is capable of function following extracellular stimulation, it could not be activated via the inside-out signaling...
ITGB3 (Integrin beta 3), also called GP3A, GPIIIa, CD61, is a protein that in humans is encoded by the ITGB3 gene. It is a cluster of differentiation found on thrombocytes. The ITGB3 complex belongs to the integrin class of cell adhesion molecule receptors that share a common heterodimeric structure with alpha and beta subunits. The ITGB3 complex mediates platelet aggregation by acting as a receptor for fibrinogen. Although the protein is expressed on the cell surface at normal levels and is capable of function following extracellular stimulation, it could not be activated via the inside-out signaling...
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Safety & Storage
Storage Temperature
After reconstitution, the Integrin beta 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Safety Statement
This Integrin beta 3 antibody is available for research use only.
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Technical Documents
Specifications
CLASS
Primary Antibodies
*USAGE / SAFETY STATEMENT
This Integrin beta 3 antibody is available for research use only.
FORMAT
Antigen affinity purified
SUBCLASS
Polyclonal
UNIPROT ID
P05106
APPLICATION.1
WB, IHC-P, FACS
HOST SPECIES
Rabbit
ISOTYPE
Rabbit IgG
REACTIVITY SPECIES
Human, Mouse, Rat
CLONALITY
Polyclonal (rabbit origin)
PURIFICATION
Antigen affinity
IMMUNOGEN
An amino acid sequence from the C-terminus of human Integrin beta 3 (EFAKFEEERARAKWDTANN) was used as the immunogen for this Integrin beta 3 antibody (100% homologous in human, mouse and rat).
STORAGE BUFFER
0.5mg/ml if reconstituted with 0.2ml sterile DI water
APPLICATION DETAILS
Western blot: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml,Flow cytometry: 1-3ug/million cells
APPLICATION NOTES
The stated application concentrations are suggested starting amounts. Titration of the Integrin beta 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Western blot testing of Integrin beta 3 antibody and Lane 1: Jurkat; 2: Raji; 3: CEM; 4: COLO320 cell lysate
Western blot testing of Integrin beta 3 antibody and Lane 1: Jurkat; 2: Raji; 3: CEM; 4: COLO320 cell lysate
IHC-P: Integrin beta 3 antibody testing of human breast cancer tissue
Flow cytometry testing of human PBM cells with Integrin beta 3 antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Integrin beta 3 antibody.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
After reconstitution, the Integrin beta 3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
Safety Statement
This Integrin beta 3 antibody is available for research use only.
Regulatory & Compliance
Badge
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