MCM2 Antibody
SKU / CAT#: F51683-0.08ML
$16500
usd
$165.00
F51683-0.08ML

MCM2 Antibody

NSJ Bioreagents
SKU / CAT#: F51683-0.08ML
MPN: F51683-0.08ML
$16500
usd
$165.00
Available
SHIPS Jun 2nd
Available
SHIPS Jun 2nd
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Description
MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
MCM2 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein forms a complex with MCM4, 6, and 7, and has been shown to regulate the helicase activity of the complex. This protein is phosphorylated, and thus regulated by, protein kinases CDC2 and CDC7.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the MCM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This MCM2 antibody is available for research use only.
Regulatory & Compliance
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Technical Documents
Specifications
CLASS
Primary Antibodies
SUBCLASS
Polyclonal
UNIPROT ID
P49736
*USAGE / SAFETY STATEMENT
This MCM2 antibody is available for research use only.
FORMAT
Antigen affinity purified
APPLICATION.1
WB, IHC, ELISA
HOST SPECIES
Rabbit
ISOTYPE
Rabbit Ig
REACTIVITY SPECIES
Human, Mouse
CLONALITY
Polyclonal (rabbit origin)
PURIFICATION
Antigen affinity
IMMUNOGEN
A portion of amino acids 649-677 from the human protein was used as the immunogen for this MCM2 antibody.
STORAGE BUFFER
In 1X PBS, pH 7.4, with 0.09% sodium azide
REACTIVITY SPECIES (PREDICTED SPECIES)
Xenopus
APPLICATION DETAILS
Western blot: 1:1000-2000,IHC (Paraffin): 1:50-1:100
APPLICATION NOTES
Titration of the MCM2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Western blot testing of MCM2 antibody at 1:2000 dilution. Lane 1: Jurkat lysate; 2: MCF-7 lysate; 3: NIH3T3 lysate; Predicted molecular weight : 102 kDa.
Western blot testing of MCM2 antibody at 1:2000 dilution. Lane 1: Jurkat lysate; 2: MCF-7 lysate; 3: NIH3T3 lysate; Predicted molecular weight : 102 kDa.
Western blot analysis of MCM2 antibody and HL-60 lysate
MCM2 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma.
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Aliquot the MCM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Safety Statement
This MCM2 antibody is available for research use only.
Regulatory & Compliance
Badge
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