Brain-derived neurotrophic factor (BDNF) is a growth factor derived from the brain that binds to TrkB receptors, regulating neuronal growth, survival, and synaptic function. PG-003, an alternative peptide to BDNF, is a chemically-synthesized homodimeric cyclic peptide with specific binding ability against the TrkB receptor.
Upon binding, PG-003 induces dimerization of the TrkB receptor, triggering subsequent signaling events in cells as a TrkB agonist. It should be noted that PG-003 is believed to have no binding or agonistic activity towards the p75 receptor, which is a low-affinity nerve growth...
Brain-derived neurotrophic factor (BDNF) is a growth factor derived from the brain that binds to TrkB receptors, regulating neuronal growth, survival, and synaptic function. PG-003, an alternative peptide to BDNF, is a chemically-synthesized homodimeric cyclic peptide with specific binding ability against the TrkB receptor.
Upon binding, PG-003 induces dimerization of the TrkB receptor, triggering subsequent signaling events in cells as a TrkB agonist. It should be noted that PG-003 is believed to have no binding or agonistic activity towards the p75 receptor, which is a low-affinity nerve growth...
Shipping & Handling
Shipped In
COLD PACKS
Safety & Storage
Storage Temperature
less than or equal to -20 degrees C (freezer)
Safety Statement
For laboratory research and development purposes only.
Please note that this product is intended for research use only and should not be used on or administrated to humans or animals. For customers in Canada, we can provide the template of end use letter in case you are inquired by Health Canada about the end use.
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