Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
Specifications
COUNTRY OF ORIGIN
China
GENE ID
https://www.ncbi.nlm.nih.gov/gene/113878;
*USAGE / SAFETY STATEMENT
For laboratory research and development purposes only.
APPLICATION.1
IHC
ANTIBODY TYPE
Polyclonal
HOST SPECIES
Rabbit
REACTIVITY SPECIES
Hu
PURIFICATION
Antigen affinity purification.
GENE ALIAS
DTX2
IMMUNOGEN
Fusion protein corresponding to residues near the C terminal of human deltex homolog 2 (Drosophila)
SPECIFICITY
The antibody detects endogenous levels of total DTX2 protein.
SWISS-PROT NO.
Q86UW9
BACKGROUND
DTX2 functions as an E3 ubiquitin ligase. Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
ALTERNAME
RNF58
FORM OF ANTIBODY
Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
RECOMMENDED DILUTIONS
Immunohistochemistry: 1:10-1:50
Questions & Answers (0)
Citations (0)
Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Safety Statement
For laboratory research and development purposes only.
Regulatory & Compliance
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