Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
Pembrolizumab biosimilar is a humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands, PD-L1 and PD-L2. It is an IgG4 kappa immunoglobulin with an approximate molecular weight of 149 kDa.
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Safety & Storage
Storage Temperature
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
PURITY
>95% by SDS-PAGE and HPLC
CONCENTRATION
5mg/ml
APPLICATION.1
Functional Assays
HOST SPECIES
Humanized
ISOTYPE
Human IgG4
REACTIVITY SPECIES
Human
PURIFICATION
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
FORMULATION
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
SPECIFICITY
Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Toripalimab.
STORAGE BUFFER
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
APPLICATION NOTES
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Endotoxin
≤ 0.5 EU/mg as determined by the LAL method
Target
PD-1
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
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