Anti-Mouse TCR Gamma/Delta (UC7-13D5) In Vivo Antibody - Low Endotoxin
SKU / CAT#: ICH1035-50mg
$2,01000
usd$40.20/mg
Anti-Mouse TCR Gamma/Delta (UC7-13D5) In Vivo Antibody - Low Endotoxin
Ichorbio Ltd.SKU / CAT#: ICH1035-50mg
MPN:
$2,01000
usd$40.20/mg
Available
SHIPS Jun 9th
Available
SHIPS Jun 9th
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Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an alpha and beta chain in 95% of T cells, while 5% of T cells have TCRs consisting of gamma and delta chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
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Safety & Storage
Storage Temperature
anti-TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
Technical Documents
Datasheet (1)
Specifications
COUNTRY OF ORIGIN
United Kingdom
CLONE NUMBER
UC7-13D5
*USAGE / SAFETY STATEMENT
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
PURITY
>95% by SDS-PAGE and HPLC
CONCENTRATION
1.0 - 5.0 mg/ml
APPLICATION.1
Flow Cytometry, Immunoprecipitation, In vivo Depletion
HOST SPECIES
Armenian Hamster
ISOTYPE
Armenian Hamster IgG
REACTIVITY SPECIES
Mouse
FORMULATION
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
IMMUNOGEN
Unknown
SPECIFICITY
The anti-mouse γ/δ T-cell receptor antibody reacts with all mouse TCR γ/δ heterodimers.
STORAGE BUFFER
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
APPLICATION NOTES
In vivo Depletion: This Clone UC7-13D5 has been used for the depletion of TCR gamma/delta T cells in vivo
Each investigator should determine their own optimal working dilution for specific applications.
Antigen Distribution
gamma/delta TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The gamma/delta TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
Aggregation
Aggregation level ≤ 5%
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Target
TCR gamma/delta
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
anti-TCR gamma/delta In Vivo Antibody - Low Endotoxin (UC7-13D5) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
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