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Bulk Anti-Human CD2 (G11) Antibody
SKU / CAT#: ICH1001-25mg
$1,26000
usd
$50.40/mg
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ICH1001-25mg

Bulk Anti-Human CD2 (G11) Antibody

Ichorbio Ltd.
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SKU / CAT#: ICH1001-25mg
MPN:
$1,26000
usd
$50.40/mg
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Available
SHIPS Jul 18th
Available
SHIPS Jul 18th
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Description
Appropriate pairs of anti-CD2 antibodies will stimulate peripheral T-cell proliferation and effector function. The CD2 molecule has been shown to be the receptor for leukocyte function antigen (LFA-3/CD58), the binding of which augments T-cell activation mediated by the T-cell antigen receptor (TCR). Anti-Human CD2 can be used to deplete CD2 positive cells by complement-mediated cytotoxicity. Analyses of NK lymphocyte subsets and identification of lymphomas and leukemias of T-cell origin have been done using Anti-CD2 antibodies.
Appropriate pairs of anti-CD2 antibodies will stimulate peripheral T-cell proliferation and effector function. The CD2 molecule has been shown to be the receptor for leukocyte function antigen (LFA-3/CD58), the binding of which augments T-cell activation mediated by the T-cell antigen receptor (TCR). Anti-Human CD2 can be used to deplete CD2 positive cells by complement-mediated cytotoxicity. Analyses of NK lymphocyte subsets and identification of lymphomas and leukemias of T-cell origin have been done using Anti-CD2 antibodies.
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Safety & Storage
Storage Temperature
anti-CD2 In Vivo Antibody - Low Endotoxin (G11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
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Technical Documents
Datasheet (1)
UNvpQ
Specifications
COUNTRY OF ORIGIN
United Kingdom
UNIPROT ID
P06729
CLONE NUMBER
G11
*USAGE / SAFETY STATEMENT
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
PURITY
>95% by SDS-PAGE and HPLC
CONCENTRATION
≥ 5.0 mg/ml
APPLICATION.1
Western Blot, Functional Assays
HOST SPECIES
Mouse
ISOTYPE
Mouse IgG2a
REACTIVITY SPECIES
Human
PURIFICATION
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
FORMULATION
0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
SPECIFICITY
Anti-CD2 In Vivo Antibody - Low Endotoxin (G11) recognizes Human CD2. Anti-Human CD2 recognizes a cell surface glycoprotein (Mr 45-59 kDa) on human lymphocytes
STORAGE BUFFER
ICH3001-100ml ICH3002-100ml ICH3003-100ml
APPLICATION NOTES
Each investigator should determine their own optimal working dilution for specific applications.
Antigen Distribution
The CD2 antigen is present on approximately 80% of normal peripheral blood lymphocytes, >95% of thymocytes, 100% of mature circulating T-cells and a subset of NK cells.
Aggregation
Aggregation level ≤ 5%
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Target
CD2
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Shipping & Handling
Shipped In
Cold Packs
Safety & Storage
Storage Temperature
anti-CD2 In Vivo Antibody - Low Endotoxin (G11) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Safety Statement
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Regulatory & Compliance
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