Byakangelicin is a coumarin that has been found in A. dahurica and has diverse biological activities. It inhibits the activity of aldose reductase (IC50 = 6.2 µM for the bovine lens enzyme) and reduces cataract formation in a rat model of galactosemia when administered at a dose of 50 mg/kg per day. Byakangelicin (30 µM) decreases LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) in isolated rat peritoneal macrophages. It reduces cartilage erosion and loss of proteoglycan in the inflamed joints in a mouse model of surgically induced osteoarthritis when administered at a dose of...
Byakangelicin is a coumarin that has been found in A. dahurica and has diverse biological activities. It inhibits the activity of aldose reductase (IC50 = 6.2 µM for the bovine lens enzyme) and reduces cataract formation in a rat model of galactosemia when administered at a dose of 50 mg/kg per day. Byakangelicin (30 µM) decreases LPS-induced production of prostaglandin E2 (PGE2; Item No. 14010) in isolated rat peritoneal macrophages. It reduces cartilage erosion and loss of proteoglycan in the inflamed joints in a mouse model of surgically induced osteoarthritis when administered at a dose of...
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Room Temperature in continental US; may vary elsewhere
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Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
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