diABZI STING agonist-3 is an agonist of stimulator of interferon genes (STING). It binds to STING (IC50 = 0.32 nM in a FRET assay) and induces STING transcriptional activity in a reporter assay (EC50 = 31.62 nM). diABZI STING agonist-3 increases protein levels of Nod-like receptor protein 3 (NLRP3), IL-1β, and IL-18, but not cGAS or mtDNA, in macrophages.
diABZI STING agonist-3 is an agonist of stimulator of interferon genes (STING). It binds to STING (IC50 = 0.32 nM in a FRET assay) and induces STING transcriptional activity in a reporter assay (EC50 = 31.62 nM). diABZI STING agonist-3 increases protein levels of Nod-like receptor protein 3 (NLRP3), IL-1β, and IL-18, but not cGAS or mtDNA, in macrophages.
Shipping & Handling
Shipped In
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Room Temperature in continental US; may vary elsewhere
Safety & Storage
Storage Temperature
-20°C
Safety Statement
WARNING This product is not for human or veterinary use. Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.
Regulatory & Compliance
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.
We’re currently in BETA - Interested in joining? Let us know and we’ll get you set up with early access.